Patient information leaflet

Description and composition

Olyfrin is an opaque liquid of white-yellow color, slightly oily with citrus aroma. 1 ml contains: anhydrous glycerol – 62.5mg, sodium benzoate – 5.0 mg, sodium hyaluronate – 1.9 mg, polysorbate 80 (tween 80) – 1.9 mg, macrogol glyceryl hydroxystearate 40 – 0.6 mg, lemon essential oil – 0.6 mg, racemic alphatocopherol acetate – 0.1 mg, water for injection – up to 1 ml.

Therapeutic indications

Otorhinolaryngology. The solution for nasal cavity care.


The solution moisturizes and eliminates symptoms of dryness (irritation, itching and burning). Due to the sodium hyaluronate in its composition it creates a protective barrier in the nasal mucosa. For children from 3 years old and adults. Hyaluronic acid is a natural polymer presented throughout the human body. Its lubricating and moisturizing properties and the necessary viscosity contribute to the formation of protective film in a nasal cavity. It provides smooth and long-lasting moistening of the nasal mucosa and protects it from adverse environmental factors. The solution also contains all-racemic alpha tocopherol acetate (Vitamin E) that provides an anti-inflammatory effect due to its antioxidant properties.

Indications for use

The solution can be used for adults and children from 3 years:

  • to create a protective barrier and to moisturize a nasal mucosa;
  • to remove excess secretions and crusts in the nasal cavity;
  • to eliminate symptoms of dryness (irritation, itching, burning) in the nasal mucosa caused by environmental exposure, dry air (conditioning, heating) or post-operative healing;
  • in case of increased bleeding, caused by the thinning and dryness of the nasal mucosa;
  • to accelerate regeneration process after surgeries;
  • in case of prolonged use of vasoconstriction medications and changed mucous membrane.

Contraindications for use

  • individual intolerance to the components of the solution;
  • complete obstruction of the nasal passages.

Recommended dosage

1-2 sprays into each nostril 1-3 times per day or as needed. Duration and frequency of solution use is not limited.

Storage conditions

Store at temperature from + 5 °C to + 25 °C, keep out of reach of children.

Shelf life

3 years. Do not use after expiration date.


Grotex LLC, Russian Federation

195279, Saint Petersburg, Industrialny av. 71, bld. 2, lit. A

Tel.: +7 812 385 47 87

Fax: +7 812 385 47 88

Olyphrin, nasal spray, 15 ml

Consult your healthcare professional before use